2 D Gel Electrophoresis System

      Description


      Unleash Unprecedented Resolution: The [Your Brand Name] Advanced 2D Gel Electrophoresis System

      Revolutionize your proteomics research with the [Your Brand Name] 2D Gel Electrophoresis System, a comprehensive and robust solution designed for the high-resolution separation of complex protein mixtures. Engineered for superior performance, reproducibility, and ease of use, this system provides an unparalleled platform for biomarker discovery, protein profiling, and post-translational modification analysis.

      Key Features & Benefits

      Our 2D Gel Electrophoresis System integrates cutting-edge technology for both isoelectric focusing (IEF) and SDS-PAGE, ensuring optimal results at every stage.

      First Dimension: Isoelectric Focusing (IEF) Module

      • Precision Temperature Control: Integrated Peltier-driven heating and cooling system maintains precise and uniform temperatures (e.g., 4-40°C with ±0.1°C accuracy) across the entire IPG strip, preventing protein degradation and ensuring consistent focusing.
      • High-Capacity Focusing: Accommodates multiple IPG strips (e.g., 12 or 24 strips) simultaneously, from 7 cm to 24 cm, maximizing throughput and enabling direct comparison of multiple samples under identical conditions.
      • Programmable Voltage Ramps: User-friendly interface allows for the creation and storage of complex voltage programs (e.g., step, ramp, hold) up to 10,000 V-hrs, facilitating optimal focusing for various sample types and IPG strip lengths.
      • Intuitive Touchscreen Interface: Large, high-resolution touchscreen provides real-time monitoring of voltage, current, and temperature, alongside easy program setup and recall.
      • Automatic Current Shut-off: Protects samples and equipment by terminating runs if current limits are exceeded, indicating issues like poor sample conductivity or a short circuit.

      Second Dimension: SDS-PAGE Gel Electrophoresis Module

      • Dual Gel Capacity: Run two standard-sized mini (e.g., 10 x 10 cm), midi (e.g., 15 x 15 cm), or maxi (e.g., 20 x 20 cm) gels simultaneously, maximizing sample throughput and ensuring consistent electrophoretic conditions.
      • Uniform Cooling System: Integrated high-capacity cooling core (e.g., connectable to an external chiller) ensures consistent gel temperatures throughout the run, preventing "smiling" effects and promoting straight, reproducible band migration.
      • Leak-Free Design: Precision-engineered gaskets and clamping mechanisms guarantee a tight seal, preventing buffer leakage and ensuring even buffer distribution.
      • Effortless Gel Casting: Includes specialized casting stands and accessories for quick, bubble-free, and reproducible gel preparation, whether using pre-cast or hand-cast gels.
      • Robust Construction: Manufactured from high-quality, chemical-resistant materials (e.g., durable acrylic or polycarbonate) for long-lasting performance in demanding laboratory environments.
      • Safety Interlocks: Built-in safety features prevent operation without the lid securely in place, protecting users from high voltage exposure.

      Integrated Power Supplies (Optional, or often bundled)

      • Dedicated IEF Power Supply: Optimized for high voltage (up to 10,000 V) and low current, crucial for achieving sharp protein focusing during IEF.
      • Versatile SDS-PAGE Power Supply: Provides stable voltage and current (e.g., up to 500 V, 500 mA, 150 W) suitable for various gel sizes and separation requirements.
      • Programmable Modes: Constant voltage, current, or power modes with automatic cross-over for maximum flexibility and sample protection.

      Applications

      The [Your Brand Name] 2D Gel Electrophoresis System is an indispensable tool for a wide range of life science applications, including:

      • Comparative Proteomics: Identify differentially expressed proteins between healthy and diseased states, or treated vs. untreated samples.
      • Biomarker Discovery: Pinpoint potential diagnostic or prognostic protein markers in complex biological fluids.
      • Post-Translational Modification (PTM) Analysis: Visualize and analyze protein isoforms resulting from phosphorylation, glycosylation, acetylation, etc.
      • Protein Purification & Characterization: Assess protein purity and identify protein components in complex mixtures.
      • Drug Discovery & Development: Evaluate the effects of drug candidates on protein expression profiles.
      • Quality Control: Monitor protein stability, degradation, and purity in biopharmaceutical production.

      Technical Specifications

      FeatureIEF Module (e.g., [Your Model Number])SDS-PAGE Module (e.g., [Your Model Number])
      IPG Strip Compatibility7 cm - 24 cm, 12 or 24 strips per runMini (10x10 cm), Midi (15x15 cm), or Maxi (20x20 cm) gel formats (specify)
      Temperature ControlPeltier-driven, 4°C to 40°C, ±0.1°C accuracyExternal chiller connectivity, uniform buffer circulation
      Voltage Range50 - 10,000 V (programmable)Up to 500 V (dependent on power supply)
      Current Range0 - 100 µA per strip (typical), 500 µA totalUp to 500 mA (dependent on power supply)
      V-Hr SettingUp to 100,000 V-hrsNot applicable
      Display7-inch color touchscreenN/A (controls on power supply)
      Program Storage20+ user-defined programsN/A
      Buffer Volume (Inner/Outer)N/AApprox. 250 mL / 1500 mL (for mini-vertical)
      Construction MaterialCorrosion-resistant aluminum, durable plasticsHigh-impact acrylic/polycarbonate, platinum electrodes
      Dimensions (W x D x H)E.g., 35 x 30 x 15 cmE.g., 20 x 15 x 25 cm (for mini-vertical)
      WeightE.g., 7 kgE.g., 2 kg (for mini-vertical)
      Power Requirements100-240 VAC, 50/60 Hz, 200WN/A (powered by external power supply)
      Safety CertificationsCE, UL, RoHSCE, UL, RoHS

      What's Included

      The [Your Brand Name] 2D Gel Electrophoresis System typically includes:

      • [Your Model Name] IEF Unit with integrated power supply and cooling
      • [Your Model Name] Dual Vertical SDS-PAGE Unit
      • Gel Casting Stand and sealing gaskets
      • (2x) Sets of Glass Plates with bonded spacers (e.g., 0.75 mm or 1.0 mm)
      • (2x) 10-Well Combs (e.g., 0.75 mm or 1.0 mm thick)
      • Buffer Dam for single gel runs
      • Power Cords
      • Comprehensive User Manual
      • Optional: Starter kit of IPG strips, rehydration buffer, and basic reagents

      Optional Accessories & Consumables

      Enhance your system and ensure continuous operation with our range of compatible accessories:

      • External Chiller/Recirculator: For precise temperature control of the SDS-PAGE unit.
      • Additional IPG Strips: A variety of pH ranges and lengths.
      • Electrophoresis Grade Reagents: Urea, thiourea, detergents, buffers, acrylamide solutions.
      • Gel Imaging System: For documentation and analysis of separated proteins.
      • Densitometry Software: For quantitative analysis of protein spots.
      • Replacement Gaskets, Spacers, and Combs: For various gel thicknesses and well configurations.
      • Protein Standards & Ladders: For molecular weight calibration.

      Why Choose [Your Brand Name]?

      • Unmatched Resolution: Our system delivers superior spot separation, allowing detection of subtle protein changes.
      • Exceptional Reproducibility: Consistent conditions across runs minimize variability, crucial for reliable research data.
      • User-Friendly Design: Intuitive controls and robust engineering simplify complex 2D techniques, making it accessible for all skill levels.
      • Durability & Reliability: Built to last, providing years of trouble-free operation in high-throughput environments.
      • Expert Support: Access to our dedicated team of technical specialists for application and troubleshooting assistance.

      Elevate your proteomics research to new heights. Discover the power and precision of the [Your Brand Name] 2D Gel Electrophoresis System today.

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